Phase 1 trial triggers $1M payment for ImmunoGen

Fri, 06/25/2010 - 5:34am
Mass High Tech: The Journal of New England Technology

Biotech firm ImmunoGen Inc. is in line for a $1 million milestone payment from sanofi-aventis, now that sanofi has launched a Phase 1 clinical trial of ImmunoGen’s SAR650984 investigational antibody.

The antibody targets cancer cells expressing the CD38 protein antigen and was developed under a five-year research collaboration between Waltham-based ImmunoGen and sanofi. It is being evaluated as a possible treatment for various blood tumors, including lymphocytic leukemia, myeloid leukemia, multiple myeloma and non-Hodgkin’s lymphoma.

According to ImmunoGen, preclinical testing has shown SAR650984 to be an effective anticancer agent. It is being evaluated in a Phase I, dose-escalation trial to establish its maximum tolerated dose and dose-limiting toxicities.

Last month, ImmunoGen (Nasdaq: IMGN) announced that it planned a $64.7 million stock offering.





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