New Study Reveals Collagenase SANTYL® Ointment More Effective Than Hydrogel Dressing for Pressure Ulcer Debridement

Thu, 09/30/2010 - 10:32am

FORT WORTH, Texas, Sept. 30 /PRNewswire/ -- Healthpoint today announced that the results of a new study conducted by Catherine T. Milne APRN, MSN, CWOCN, BC-ANP, will be presented on Thursday, September 30, 2010 at 7:15pm (Eastern) at the Healthpoint booth (#110) during the 25th Annual Clinical Symposium on Advances in Skin & Wound Care: The Conference for Prevention and Healing. The conference is being held from September 30 to October 3, 2010, at the Gaylord Palms Resort & Convention Center in Orlando, Florida. Ms. Milne will also deliver encore presentations of her study results at 11:15am (Eastern) on Friday, October 1st, and 12:45pm (Eastern) on Saturday, October 2nd; all presentations will be held in The Wound Institute® Theatre located inside of the Healthpoint booth.

The study was designed to evaluate the comparative efficacy of Collagenase SANTYL® Ointment to a hydrogel dressing as measured by time to complete wound debridement (dead tissue removal) of pressure ulcers. Twenty-seven nursing home residents were enrolled and randomized to receive either Collagenase SANTYL® Ointment (N=13) -- an enzymatic debriding agent -- or a hydrogel dressing (N=14). Investigators blinded to randomization evaluated weekly wound photographs using a digital planimetry software package for debridement. The Collagenase-treated group achieved statistical significance in complete debridement by day 42 as compared to the hydrogel-treated group (p<.003); eleven of the 13 Collagenase-treated patients (85%) vs. four of the 14 hydrogel-treated patients (29%) experienced complete debridement by day 42.

"To date, studies comparing Collagenase to hydrogel have not been reported in the literature," noted Catherine T. Milne, APRN, MSN, CWOCN of the Bristol Hospital Wound, Ostomy, Lymphedema Center in Bristol, Connecticut and the study's principal investigator. "The findings of the present study are particularly relevant for clinicians in the long





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