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Duncan Cancer Center researchers bring in more than $8 million in fourth round of state cancer funding

Mon, 11/08/2010 - 1:37pm
Baylor College of Medicine
HOUSTON -- (November 8, 2010) -- Researchers from the NCI-designated Dan L. Duncan Cancer Center at Baylor College of Medicine have been awarded 11 new research projects totaling more than $8 million in the fourth round of recently awarded Cancer Prevention Research Institute of Texas grants.

In this round, the institutions receiving the most funding were The University of Texas Southwestern Medical Center, $13,281,082; MD Anderson Cancer Center, $11,769,096; and BCM, $8,307,356.

To date, Duncan Cancer Center researchers have been awarded more than $38 million in CPRIT funding.

"Our team possesses a tremendous amount of knowledge and creativity that has the potential to greatly advance cancer research," said Dr. C. Kent Osborne, director of the Dan L. Duncan Cancer Center. "Support such as this helps us to harvest that potential."

The BCM recipients include:

  • Dr. Leonid Metelitsa, associate professor of pediatrics – hematology/oncology in the Texas Children's Cancer Center, for a project entitled "Genetic Engineering of Universal NKT Cells for Cancer Immunotherapy"
  • Dr. David Tweardy, professor of medicine – infectious diseases, for a project entitled "Targeting Oncoprotein Folding Intermediates to Treat Cancer"
  • Dr. Xin Li, assistant professor of molecular and cellular biology, for a project entitled "The miR-200 family and metastatic prostate cancer"
  • Dr. Margaret Goodell, director of the Stem Cells and Regenerative Medicine Center and professor of pediatrics – hematology/oncology in the Texas Children's Cancer Center, for a project entitled "Role of DNA Methylgransferase 3B in normal and malignant hematopoiesis"
  • Dr. Lawrence Donehower, professor of virology and microbiology, for a project entitled "Inhibition of the Wip1 oncogenic phosphatase as an anti-cancer strategy"
  • Dr. Yongcheng Song, assistant professor of pharmacology, for a project entitled "Novel Epigenetic Modulators Targeting Leukemia Initiating Cells"
  • Dr. Hoang Nguyen, assistant professor of molecular and cellular biology, for a project entitled "The role of Tcf3 in skin squamous cell carcinoma"
  • Dr. Chrystal Louis, assistant professor of pediatrics – hematology/oncology in the Texas Children's Cancer Center, for a project entitled "Chemo-immunotherapy for Relapsed or Refractory Nasopharyngeal Carcinoma"
  • Dr. Jed Nuchtern, assistant professor of pediatrics – surgery and a researcher in the Texas Children's Cancer Center, for a project entitled "Neuroblastoma-Derived Secretory Protein Receptor, a New Target for Neuroblastoma Therapy"
  • Dr. Orla Conneely, professor of molecular and cellular biology, for a project entitled "Discovery of Small Molecule Activators of NR4A Orphan Nuclear Receptors for Treatment of Acute myeloid Leukemia"
  • Dr. Adriano Flora, assistant professor of molecular and human genetics, for a project entitled "A functional genetic approach to identify new potential therapeutic targets for medulloblastoma"

In addition to these projects, Duncan Cancer Center researchers will be involved in multi-institutional projects led by other institutions, including an ovarian cancer project with Dr. Matthew Anderson, assistant professor of obstetrics and gynecology, and the University of Houston.

The Texas Children's Cancer Center is a joint program of Baylor College of Medicine and Texas Children's Hospital and is the pediatric cancer program of the Dan L. Duncan Cancer Center.

Find more information on all of BCM's CPRIT projects.

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