WALTHAM, Mass., March 31, 2011 /PRNewswire/ -- Syndax Pharmaceuticals, Inc., a clinical-stage epigenetics oncology company, today announced 11 posters on entinostat, an oral, highly selective, class I histone deacetylase (HDAC) inhibitor, will be presented at the 102nd Annual American Association for Cancer Research meeting April 2 to April 6 in Orlando, FL.

"The breadth of exciting data being presented at AACR provides additional insight into the opportunities for Syndax to build out our entinostat development program," said Joanna Horobin, president and chief executive officer of Syndax. "The AACR presentations add to the growing body of evidence supporting the potential for entinostat in solid tumors including the promising results with entinostat in combination with Tarceva® in advanced non-small-cell lung cancer which were presented at the end of last year. Recently we completed our randomized, placebo-controlled phase 2 clinical trial in metastatic breast cancer which will be presented at a scientific conference later this year and are aggressively moving forward with a pivotal program in this patient population." The following posters will be presented Monday, April 4: Time:

8:00 AM to 12:00 PM EDT: Presentation #:

1146 Title:

Multiple HDAC inhibitors (HDACi) reduce the expression of the oncogenic miR-17~92 cluster; a pan HDACi class effect Location:

Exhibit Hall A4-C, Poster Section 7 Time:

8:00 AM to 12:00 PM EDT: Presentation #:

1792 Title:

Selective class I HDAC inhibitor SNDX-275 enhances anti-tumor survivin vaccine therapy by suppressing regulatory T cells in a model of prostate cancer Location:

Exhibit Hall A4-C, Poster Section 32 Time:

1:00 to 5:00 PM EDT: Presentation #:

2018 Title:

Combination therapy with vidaza and entinostat suppresses tumor growth and reprograms the epigenome in an orthotopic lung cancer model Location:

Exhibit Hall A4