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New Study Explores Impact of More Uniform Distribution of Endovascular Coils in Cerebral Aneurysm Treatment

Tue, 06/21/2011 - 10:43am
Bio-Medicine.Org

RAYNHAM, Mass., June 21, 2011 /PRNewswire/ -- A new study published in the June edition of the Journal of NeuroInterventional Surgery(1) highlights that a more uniform distribution of endovascular coils may help in the treatment of cerebral aneurysms, it was reported by Codman & Shurtleff, Inc. (Codman), a global neurovascular and neuroscience company.  Codman's DELTAPAQ™ endovascular microcoils were used in the study.

Study authors found that the novel triangular primary wind design of DELTAPAQ™ endovascular microcoils achieved a tighter packing density and a more uniform distribution of the coil mass across the aneurysm dome in comparison with helical and complex endovascular microcoils.  DELTAPAQ coils were also more likely to have the highest rate of angiographic occlusion.  

Researchers concluded that the evaluation of emerging coil technologies with respect to treatment durability may be well served by an assessment of their uniformity of distribution within an aneurysm, in addition to the traditional packing density and angiographic occlusion scoring methods.  

"This study suggests that the uniformity across the dome of the aneurysm may play an important role in enhancing the durability of endovascular treatment and is an important area for further study and confirmation," said Bernard R. Bendok, MD, study co-author and Associate Professor of Neurological Surgery and Radiology at Northwestern University's Feinberg School of Medicine.*  "The application of a coil uniformity model may provide valuable design information."  

Study authors constructed silicone aneurysm models and devised an assessment tool to objectively measure the coil uniformity index, which when combined with the degree of angiographic occlusion and packing density, can provide valuable information regarding coil behavior.

In the in vitro study, DELTAPAQ coils were more uniformly distributed in the dome of t

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