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BSGI/MBI Shows Greater Sensitivity and Comparable Specificity When Compared to Ultrasound and Mammography

Tue, 11/29/2011 - 4:38am
Bio-Medicine.Org

NEWPORT NEWS, Va., Nov. 29, 2011 /PRNewswire/ -- When compared to mammography and ultrasound, Breast-Specific Gamma Imaging (BSGI), also known as Molecular Breast Imaging (MBI), has greater sensitivity and comparable specificity according to a new study that will be presented at the 2011 Radiological Society of North America (RSNA) annual meeting to be held in Chicago, Nov. 27 through Dec. 2, 2011. BSGI/MBI also proved to be a valuable adjunctive procedure when mammography and ultrasound fail to provide a confident breast cancer diagnosis.

"This study helped show the power of BSGI, especially in patients with indeterminate results on mammography or ultrasound," said Jean Weigert, M.D., first author on the study. "Many suspicious areas can show up on an ultrasound. BSGI helps us focus on the areas of true positive and determine where to biopsy."

Four institutions participated in the study to compare BSGI/MBI to mammography (MMG) and ultrasound (US) in patients who required diagnostic imaging due to clinical or radiographic findings.  The researchers on the study include radiologists Jean M. Weigert of Bradley Memorial Hospital in New Britain, Conn.; Margaret L. Bertrand of the Solis Bertrand Breast Center in Greensboro, N.C.;  Leora Lanzkowsky of Nevada Imaging in Las Vegas, Nev.; Lillian H. Stern of Methodist Hospital in Philadelphia.

For this study BSGI/MBI was conducted with a high-resolution gamma camera, the Dilon 6800®. It was concluded that BSGI/MBI has greater sensitivity and comparable specificity compared to ultrasound and mammography, and is a valuable adjunctive procedure when these anatomical imaging modalities fail to provide a confident diagnosis. BSGI/MBI is also a useful diagnostic modality to augment mammography in the management of patients with difficult to diagnose breast tissue, and in cases where unresolved clinical concern remains after a mammogram.

"The results of the study increase my confidence

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