PathoGenetixs proprietary GSS technology combines automated sample preparation and single molecule detection making it possible to detect and characterize microbes from complex biological samples in as little as three hours. Specifically, the technology extracts genomic barcodes from microbial DNA as it flows through a microfluidic chip at 150 million base pairs per second. A universal reagent set decorates the DNA enabling specific pathogens to be identified by comparing their unique DNA â€˜barcode with PathoGenetixs own library of templates. With this approach, it is possible to identify thousands of different microbial strains through a single test, days faster and at far lower cost than current techniques. The GSS technology was developed with more than $50 million in support from the United States Departments of Defense and Homeland Security under advanced biosensor programs.
Sagentia, an experienced leader in the development of new technologies and breakthrough products, including complex diagnostics, was brought in to the project to take the current laboratory prototype and help turn it into a technically and commercially successful platform. Sagentias work will include further integration of state-of-the-art optics and microfluidics, making the technology more robust, enhancing the usability of the system, driving cost reduction, and increasing manufacturing efficiency.
"Sagentias commitment to PathoGenetix directly reflects our mission to help clients develop and deliver innovative technologies through all the stages of device development," said Brent Hudson, chief executive officer of Sagentia. "Working across the complete product development continuum - from market needs analysis to transfer to volume manufacturing - we make it possible for companies to take complex ideas and develop them into products that are robust and usable in many settings. We are excited to work with PathoGenetix and look forward to helping them bring this groundbreaking new technology to market."
"We are very excited to be working with Sagentia on this critical initiative," said John Canepa, chief executive officer of PathoGenetix. "At PathoGenetix, we are focused on revolutionizing microbial identification and diagnostics. We chose Sagentia because of the companys extensive technical knowledge and the teams understanding of our core objectives. We believe that Sagentias team will add tremendous value to this project and we look forward to working with them to bring to market an instrument platform that will improve the speed and efficacy in a range of diagnostics applications." He added that PathoGenetix expects to launch the systems initial commercial application, for the research market, in late 2012.
This is another important client project for Sagentia as the company continues to grow its US footprint. In November of 2010, Sagentia expanded its presence in the U.S. by opening an office at One Broadway Street in Cambridge, Massachusetts where the company was selected to be a member of Governor Deval Patricks U.S.-U.K. trade partnership.
Sagentia is a global innovation, technology and product development company. We provide outsourced R&D consultancy services to start ups through to global market leaders in the medical, industrial and consumer sectors.
With global headquarters in Cambridge, UK, and US headquarters in Cambridge, Massachusetts, Sagentia works with clients from front end market needs analysis through to transfer to manufacture. We deliver innovation around new technologies and new generation products and services that provide commercial value and market advantage. The company also assists business leaders to create strategies for technology, innovation and growth. Further information can be found at: www.sagentia.com. Email us firstname.lastname@example.org.
PathoGenetix is developing an automated system for the rapid identification of bacterial strains using proprietary Genome Sequence Scanning Technology. The companys approach, which employs a single reagent set to generate genomic bar codes based on bacterial DNA, can cost-effectively identify thousands of strains in a single test from complex samples in three hours. PathoGenetix is developing its GSS platform for use in genomics research, food and product safety testing, and clinical infectious disease diagnostics, with initial commercial introduction into the research market planned for late 2012. Learn more at www.pathogenetix.com.
Posted by Sean Fenske, Editor-in-Chief, MDT