Drug Targets Lupus by Tricking Immune System
Scientists developing drugs to treat lupus face a daunting set of challenges. The disease, which affects 1.5 million Americans, results when the immune system mistakenly recognizes healthy tissues as dangerous and attacks them, touching off a range of responses. Some patients get arthritis and rashes, others develop heart disease, and some suffer kidney damage that can endanger their lives. And it still isn't clear what causes all these symptoms.