NIH halts weight-loss study ahead of schedule amid positive outcomes | MassDevice.com On Call
The National Institutes of Health halted its "Look AHEAD" weight-loss trial 2 years early after finding significant benefits for both lifestyle intervention and diabetes education, but little difference between the 2.
MASSDEVICE ON CALL — The National Institutes of Health cut short the "Look AHEAD" trial 2 years ahead of schedule after demonstrating much lower rates of heart attack and strokes among both arms of the study, which involved more than 5,000 patients with diabetes who received either lifestyle intervention or diabetes education.
Both group benefited during the 11 years of follow-up, but there was little difference between the 2. The NIH and the study's Data & Safety Monitoring Board determined that it was "extremely unlikely" that a difference would develop with the 2 additional years of observation originally planned.
The patients in the study will no longer receive the interventions, but NIH plans to continue its monitoring, according to a press release .