These tamper-evident labels and seals for the medical industry are ideal for securing laboratory specimens, surgical assets, and forensic kits. Providing full traceability and legal integrity, the labels ensure that specimens cannot be altered or substituted—particularly suitable for transportation. The security labels are ideal for any application where a high-strength adhesive bond and long term stability are required. The labels can withstand chemicals, solvents and extreme temperatures. A “void” pattern or a tamper substrate can be included in the construction of the labels for increased security or to avoid counterfeiting.