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The Lead

Reducing Animal Testing for Skin Allergies

March 2, 2015 1:56 pm | by European Commission, Joint Research Centre (JRC) | News | Comments

The JRC has validated and recommended a new method which is not based on animal testing, to identify chemicals that can trigger skin allergies, estimated to affect already 20% of the population in Europe. The human Cell Line Activation Test...

Diagnosing TB with Oral Swabs

March 2, 2015 10:49 am | by University of Washington Health Sciences/UW Medicine | News | Comments

Drawing inspiration from veterinary medicine, researchers at the University of Washington have...

Lab-on-Paper for Rapid, Inexpensive Immune-Detection Tests

March 2, 2015 10:15 am | by University of Rhode Island | News | Comments

A team of University of Rhode Island engineers led by Professor Mohammad Faghri has created a...

Untangling DNA with a Droplet of Water, a Pipette and a Polymer

February 27, 2015 2:51 pm | by KU Leuven | News | Comments

Researchers have long sought an efficient way to untangle DNA in order to study its structure -...

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Device 1,000 Times More Sensitive to Biomarkers for TBI Screening

February 27, 2015 2:13 pm | by NYU Langone Medical Center | News | Comments

New technology being introduced at NYU Langone Medical Center could help researchers advance blood biomarker capabilities that show changes in low concentrations of specific proteins present following a neurological injury. The single molecule...

Urine Test Could Lead to Better Bladder Cancer Treatment

February 27, 2015 10:33 am | by University of Birmingham | News | Comments

Researchers at the University of Birmingham believe that a simple urine test could help to guide clinicians in the treatment of bladder cancer patients. Being able to reliably identify those patients with the most aggressive cancers early...

Lab Test on Tumor Cells for Personalized Cancer Treatments

February 27, 2015 9:47 am | by Dana-Farber Cancer Institute | News | Comments

By measuring how vigorously tumor cells turn on "self-destruct" signals when exposed to different cancer drugs, a novel lab test can predict within less than 24 hours which agent is most likely to work against a particular tumor, say researchers...

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Screening for Diabetes at Dental Visits Using Oral Blood

February 27, 2015 9:21 am | by New York University | News | Comments

It is estimated that 8.1 million of the 29.1 million Americans living with diabetes are undiagnosed and many who have diabetes have poor glycemic control. Given that each year many Americans visit a dental provider but not a primary care...

A New Ultrasensitive Test for Peanut Allergies

February 27, 2015 9:06 am | by University of Connecticut | News | Comments

Current peanut allergy tests are not very reliable when it comes to diagnosing the severity of an individual's allergic reaction, which can range from hives to life-threatening anaphylactic shock. With an estimated three million people...

Urine Test Predicts Heart Failure Patients’ Risk of Kidney Injury

February 27, 2015 9:00 am | by American Society of Nephrology | News | Comments

Levels of a protein in the urine may help clinicians predict which patients with acute heart failure are at increased risk of developing kidney injury during hospitalization, according to a study appearing in an upcoming issue of the Journal...

Using Blood Samples Instead of Tumor Biopsies for Lung Cancer Patients

February 26, 2015 4:31 pm | by The JAMA Network Journals | News | Comments

A study examined the feasibility of using circulating free DNA (cfDNA) from blood samples of patients with advanced non-small-cell lung cancer as a surrogate for tumor biopsies to determine tumor-causing epidermal growth factor receptor...

Zinc Test Could Help Diagnose Breast Cancer Early

February 25, 2015 10:29 am | by University of Oxford | News | Comments

A team, led by Oxford University scientists, took techniques normally used to analyze trace metal isotopes for studying climate change and planetary formation and applied them to how the human body processes metals. In a world-first the...

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Skin Test May Shed New Light on Alzheimer’s and Parkinson’s Diseases

February 25, 2015 9:17 am | by American Academy of Neurology (AAN) | News | Comments

Scientists have discovered a skin test that may shed new light on Alzheimer’s and Parkinson’s diseases, according to a study released today will be presented at the American Academy of Neurology’s 67th Annual Meeting in Washington, D.C...

Optical Nanoantennas Set the Stage for a NEMS Lab-on-a-Chip Revolution

February 24, 2015 4:07 pm | by American Institute of Physics | News | Comments

Newly developed tiny antennas, likened to spotlights on the nanoscale, offer the potential to measure food safety, identify pollutants in the air and even quickly diagnose and treat cancer, according to the Australian scientists who created...

Test Strip for Ebola, Yellow Fever, and Dengue

February 24, 2015 9:41 am | by Anne Trafton, MIT News Office | News | Comments

When diagnosing a case of Ebola, time is of the essence. However, existing diagnostic tests take at least a day or two to yield results, preventing health care workers from quickly determining whether a patient needs immediate treatment and...

FDA Eases Access to 23andMe's DNA Screening for Inherited Diseases

February 20, 2015 9:58 am | by Matthew Perrone, AP Health Writer | News | Comments

Federal health officials are easing access to DNA tests used to screen parents for devastating genetic disorders that can be passed on to their children. The surprise announcement offers a path forward for Google-backed genetic testing...

Blood Test Rules Out Heart Attacks to Reduce ER Burden

February 20, 2015 9:33 am | by Bournemouth University | News | Comments

A new test that rules out heart attacks in patients could reduce hospital admissions by as much as 40%, for patients with chest pain, according to research published by Bournemouth University (BU). The research found that a quick protocol...

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Lab Tests and Ultrasounds Identify Children Who Need Surgical Treatment for Appendicitis

February 19, 2015 1:44 pm | by American College of Surgeons | News | Comments

Data from two standard diagnostic tests commonly obtained in children evaluated for abdominal pain--when combined--can improve the ability of emergency department physicians and pediatric surgeons to identify those patients who should be...

Human Organs–on–Chips Nominated for Design of the Year 2015

February 19, 2015 9:19 am | by Wyss Institute for Biologically Inspired Engineering at Harvard | News | Comments

The Wyss Institute's human organs–on–chips have been nominated for Design of the Year 2015 by the Design Museum in London and will be put on display as part of the museum's Designs of the Year 2015 Exhibition. The Designs of the Year Exhibition...

Assessing 23andMe’s Direct to Consumer Tests

February 18, 2015 4:05 pm | by American Association for Clinical Chemistry | Videos | Comments

Consumer interest in genetic testing is on the rise, and direct-to-consumer (DTC) genetic testing presents both opportunities and challenges for the laboratory community. On Thursday, February 26th at 2PM, Linnea Baudhuin, PhD, DABMG, from...

3D Engineered Bone Marrow Makes Functioning Platelets

February 18, 2015 11:31 am | by Tufts University | News | Comments

A team led by researchers at Tufts University School of Engineering and the University of Pavia has reported development of the first three-dimensional tissue system that reproduces the complex structure and physiology of human bone marrow...

Smartphone Reader for Detecting Ebola

February 18, 2015 11:04 am | by Novarum DX | News | Comments

Novarum DX, the world’s leading mobile point of care technology company, specializing in creating smartphone apps for reading and sharing diagnostic test results, has announced it will demo a newly created app which reads a rapid, point...

Saliva Test to Diagnose Autism

February 17, 2015 10:20 am | by Clarkson University | News | Comments

A spit test may one day be able to diagnose autism according to researchers at Clarkson University and the State University of New York at Plattsburgh. Scientists at the universities have published the first study showing that children with...

FDA Clears an Alternative to Needles During Hospital Blood Draws

February 15, 2015 9:00 am | by Velano Vascular | News | Comments

Velano Vascular today announced that the U.S. Food and Drug Administration (FDA) has granted marketing clearance for a new technology that provides an innovative approach to one of the most common procedures in medicine – the in-hospital...

2-Minute Screening Test Now Required for All Newborns in Michigan

February 12, 2015 1:51 pm | by University of Michigan Health System | News | Comments

At birth, Payton was the image of perfect health - rosy cheeks, weighing 7 pounds, 15 ounces, and eating like a champ. But just minutes before parents Holly and Rob Morris expected to take her home from Hillsdale Community Health Center...

Personalizing Patient Treatments with Automated Genetic Testing

February 12, 2015 10:52 am | by Sam Brusco, Associate Editor, @SamISureAm | Blogs | Comments

Meet Bob Bean, CEO of Harmonyx Diagnostics. Also the president and CEO of Transnetyx, which provides automated genotyping services, he helped to found Harmonyx in order to provide accurate, affordable, and accessible genetic testing for...

Simple Blood Test Can Predict Risk of Dementia

February 10, 2015 10:48 am | by University of Copenhagen - The Faculty of Health and Medical Sciences | News | Comments

Scientists at Rigshopitalet, Herlev Hospital and the University of Copenhagen identify a new biomarker that can predict the risk of developing dementia by way of a simple blood test. In the long term, this could mean better prevention and thus at...

After First Molecular Rapid Test Approval, Expect More

February 9, 2015 11:34 am | by Kalorama Information | News | Comments

Kalorama Information says that the broad-use approval of the first rapid diagnostic test for influenza with a molecular basis demonstrates the potential for molecular POC marketplace predicted in the firm’s report last year.  Alere i Influenza...

FDA Considering How to Tailor its Oversight for Next Generation Sequencing

February 8, 2015 11:00 am | by Margaret A. Hamburg, M.D., Commissioner, Food and Drug Administration | Blogs | Comments

FDA is weighing the appropriate regulatory approach to advances in technology that allow physicians to obtain information on large segments of a patient’s genetic makeup very quickly. This technology is known as next generation sequencing...

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