Mayo Clinic researchers have shown that a specific protein pair may be a successful prognostic biomarker for identifying smoking-related lung cancers. The protein — ASCL1 — is associated with increased expression of the RET oncogene, a particular cancer-causing gene called RET.
Researchers at MIT have developed a microfluidic device that mimics the flow of cancer cells through a system of blood vessels. Using high-resolution time-lapse imaging, the researchers captured the moments as a cancer cell squeezes its way through a blood vessel wall into the surrounding extracellular matrix.
A new, non-invasive imaging technique, magnetic resonance elastography, can now help physicians accurately detect fibrosis in children with chronic liver disease. A new study shows that MRE detects such chronic diseases as non-alcoholic fatty liver disease, which is increasingly common in children and teens, affecting an estimated 13 percent of adolescents.
Florida Hospital Collaborates with VTT of Finland to Explore Research for Early Detection of Alzheimer’s DiseaseSeptember 19, 2013 11:36 am | by Technical Research Centre of Finland (VTT) | News | Comments
In an effort to better understand the development of Alzheimer’s disease, Florida Hospital Neuroscience Institute and VTT Technical Research Centre of Finland are collaborating to identify the biomarker assay that may predict early onsets of the disease.
It happens too often: A doctor isn't sure what's causing someone's feverish illness but prescribes antibiotics just in case, drugs that don't work if a virus is the real culprit. Now Duke University researchers are developing a blood test to more easily tell when a respiratory illness is due to a virus and not a bacterial infection, hoping to cut the dangerous overuse of antibiotics and speed the right diagnosis.
A handheld device for diagnosing the early signs of osteoporosis could be available for clinical use within five years. The technology is currently being refined and tested at the University of Southampton with support from the Engineering and Physical Sciences Research Council (EPSRC).
Imec and Panasonic are jointly developing a fully integrated sample-to-answer device to perform molecular diagnostic tests. Recently, they’ve created prototype of the device. The chip is about half the size of a credit card that performs fast, simple and sensitive detection of genetic markers, specifically single nucleotide polymorphisms (SNPs).
Scientists seeking new ways to fight cancer often try to understand the subtle, often invisible, changes to DNA, proteins, cells, and tissue that alter the body's normal biology and cause disease. Now, to aid in that fight, a team of researchers has developed a sophisticated new optical imaging tool that enables scientists to look deep within tumors and uncover their inner workings.
Life sciences is one industry that is currently undergoing a turbulent development environment. Major advancements such as next-generation DNA sequencing and molecular imaging are expected to drive growth in categories such as immunochemistry and genetic testing. Add to this that changes in government regulations and market conditions are forcing life science OEMs to build their products using faster, smaller more modular technologies.
With funding from the National Institute for Health Research, experts at The University of Nottingham have developed a highly accurate prototype technique which can produce a detailed ‘spectroscopic fingerprint’ of each tissue layer removed during surgery.
Routine screening has been touted as the most effective way to stem cancer deaths, but it may instead put patients in harm's way, according to American Cancer Society chief medical officer Dr. Otis Brawley. Speaking at a seminar last week, Brawley warned that hospitals recommending regular screening may be looking out for their profits rather than their patients.
Logical Images, the Rochester-based company that created the nation's only widely used diagnostic decision tool, VisualDx, announced today that it has been awarded a U.S. patent for its unique visual diagnostic process and system that, in addition to other features, selectively presents and displays images based upon descriptive characteristics of a patient.
A protein called isocitrate dehydrogenase (IDH1) is present at high levels in lung cancers and can be detected in the blood, making it a noninvasive diagnostic marker for lung cancers, according to a study published in Clinical Cancer Research, a journal of the American Association for Cancer Research.
Aydogan Ozcan, a professor of electrical engineering and bioengineering at the UCLA Henry Samueli School of Engineering and Applied Science, and his team have created a portable smartphone attachment that can be used to perform sophisticated field testing to detect viruses and bacteria without the need for bulky and expensive microscopes and lab equipment.
Flexpoint Sensor Systems, Inc. today announced they expect to complete both Phase Two and Phase Three of development of the colonoscope application during the remainder of 2013. The company will receive milestone cash payments for each stage of the development process.
Fraunhofer FIT demonstrates a mobile wireless system that monitors the health of elderly people in their own homes, using miniature sensors, and also a novel optical system for detecting antibiotic resistance, which can determine in just two hours if bacteria react to a specific antibiotic.
The National Institutes of Health has awarded Georgia Tech a $2-million research grant to unravel the mechanical forces at play in lymphedema, a poorly understood disease with no cure and little hope for sufferers. Lymphedema develops when the body fails to circulate lymphatic fluid, a mixture of immune cells, proteins, and lipids.
Andrew Fish, executive director of AdvaMedDx, a division of the Advanced Medical Technology Association (AdvaMed) focused on diagnostics policy matters, released the following statement on the introduction in the U.S. House of Representatives of the Modernizing Our Drug and Diagnostics Evaluation and Regulatory Network (MODDERN) Cures Act.
Just as wires must be insulated to effectively carry electrical impulses, nerve cells must be insulated by myelin to effectively transmit neural impulses. Using typical magnetic resonance imaging or MRI, one can visually distinguish parts of the brain that look white and parts that look gray.
A new EU project, METSY, develops and applies neuroimaging and bioinformatics tools to study how lipid metabolism is connected to psychotic disorders and metabolic co-morbidities such as metabolic syndrome and diabetes. The overall objective is to identify, prioritize and evaluate multi-modal blood and neuroimaging biomarkers...
Quidel Receives Two FDA Clearances for Molecular Diagnostic Tests for Use on Life Technologies QuantStudio(TM) DxSeptember 16, 2013 8:00 am | by The Associated Press | News | Comments
Quidel Corporation and Life Technologies Corporation announced today that the United States Food and Drug Administration (FDA) has granted 510(k) clearances to the Quidel Molecular Influenza A+B assay and the Quidel Molecular RSV + hMPV assay, both for use on the QuantStudio Dx Real-Time PCR Instrument by Life Technologies.
Product designer Jarl Reitan and his colleague Silje Bøthun are working on a preventative project for patients with advanced COPD. Five patients from Trondheim are currently testing a system using tablet computers and a customized app developed by SINTEF.
A Lawrence Livermore National Laboratory-developed biological detection technology has been employed as part of an international collaboration that has detected a virus in bladder cancers. The research is believed to be the first study to demonstrate an association between Kaposi's sarcoma-associated herpesvirus (KSHV), also known as human herpesvirus 8, and bladder cancers.
A team of researchers led by Jun Cheng of the A*STAR Institute for Infocomm Research, Singapore, has developed a novel automated technology that screens for glaucoma more accurately and quickly than existing methods.
The Menarini Group, a privately held Italian pharmaceutical and diagnostics company, today announced it has acquired Silicon Biosystems, S.p.A., a provider of specialized molecular and cellular biology technologies capable of recovering and analyzing tumor cells from blood samples.