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Natick medical device maker Boston Scientific Corp. said this morning that it has signed a definitive merger agreement under which it will acquire Asthmatx Inc., a Sunnyvale, Calif., company that manufactures a catheter-based bronchial thermoplasty procedure for treatment of asthma.

The deal could be worth up to $443.5 million. Boston Scientific is paying $193.5 million up front, and up to $250 million contingent of revenue-based criteria through 2019.

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