Source code developed by government employees is by definition "public domain", and therefore should be free, open, and easily available to all. To accomplish this goal, CDRH advocates that developers publish and maintain source codes in web-accessible software repositories. To promote the visibility and transparency of CDRH's computational research, developers are also encouraged to "release early and often" in accordance with open source software development philosophy. This approach creates a tight feedback loop between developers and testers or users, which results in higher quality software being developed more readily.

There are currently two CDRH computational research projects where the source code is available through external software repositories. They are:

TheraPydisclaimer icon

A collection of Python scripts developed to model the evolution of chemical and physical inhomogeneities, i.e. microstructure, in drug-polymer composites used as controlled drug release coatings. This set of tools can reduce empiricism in materials selection and process design, providing a facile and efficient means to tailor the underlying microstructure and achieve a desired drug release behavior.

MC-GPUdisclaimer icon

X-ray imaging system simulation code implementing an accurate Monte Carlo x-ray transport algorithm that can be efficiently executed in a state-of-the-art Graphics Processing Unit (GPU). MC-GPU generates clinically-realistic projection or tomographic images of the human anatomy that can be used in the assessment and optimization of imaging systems, as shown in Medical Physics 36, p. 4878-4880 (2009).

Disclaimer: This software and documentation (the "Software") were developed at the Food and Drug Administration (FDA) by employees of the Federal Government in the course of their official duties. Pursuant to Title 17, Section 105 of the United States Code, this work is not subject to copyright protection and is in the public domain. Permission is hereby granted, free of charge, to any person obtaining a copy of the Software, to deal in the Software without restriction, including without limitation the rights to use, copy, modify, merge, publish, distribute, sublicense, or sell copies of the Software or derivatives, and to permit persons to whom the Software is furnished to do so. FDA assumes no responsibility whatsoever for use by other parties of the Software, its source code, documentation or compiled executables, and makes no guarantees, expressed or implied, about its quality, reliability, or any other characteristic. Further, use of this code in no way implies endorsement by the FDA or confers any advantage in regulatory decisions. Although this software can be redistributed and/or modified freely, we ask that any derivative works bear some notice that they are derived from it, and any modified versions bear some notice that they have been modified.