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Researchers at Yale University report that they have found a gene they believe to be a key contributor to depression.

In an article published in the journal Nature Medicine, the researchers said the gene is a promising target for a new class of antidepressants. The senior author on the study, Ronald S. Duman, professor of psychiatry and pharmacology at Yale said, “This could be a primary cause, or at least a major contributing factor, to the signaling abnormalities that lead to depression.”

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