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Cambridge biotech Alnylam Pharmaceuticals Inc. is collaborating with Minneapolis-based Medtronic Inc. and California non-profit CHDI Foundation Inc. to advance a drug-device combination treatment of Huntington’s disease, a neurodegenerative genetic disorder.

The treatment, ALN-HTT, is an RNAi therapeutic that targets the huntingtin gene associated with Huntington’s disease. Medtronic developed an implantable infusion system to deliver ALN-HTT. The virtual biotech firm CHDI is focused on the discovery and development of treatments for Huntington’s disease.

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