BRIDGEWATER, N.J., Dec. 9, 2010 /PRNewswire-FirstCall/ -- Sanofi-aventis (EURONEXT: SAN and NYSE: SNY) announced today that the final survival analysis (10-year follow-up) of the BCIRG001 study that included a Taxotere® (docetaxel) Injection Concentrate chemotherapy treatment regimen in the adjuvant breast cancer setting, as well as data from iniparib (BSI-201) pre-clinical and clinical breast cancer studies will be featured during the 33rd Annual San Antonio Breast Cancer Symposium (SABCS) in San Antonio, Texas from December 8 to 12, 2010.
During SABCS, the final (10-year follow up) survival analysis of the BCIRG001 study that included sanofi-aventis' chemotherapy drug Taxotere, in combination with doxorubicin and cyclophosphamide, in women with operable node-positive breast cancer will be presented. Also being presented are data from pre-clinical and clinical studies involving the sanofi-aventis investigational compound iniparib (BSI-201), which is being studied in breast cancer. Iniparib is a novel investigational small molecule with poly (ADP-ribose) polymerase (PARP) inhibitory activity.
Key events at SABCS include: Taxotere Data:Abstract #S4-3
Friday, Dec. 10
3:45 PM CSTAn oral presentation featuring final results from the ten-year follow-up analysis of the BCIRG 001 trial Iniparib Data:Abstract #P5-06-09
Phase 1b/2 MBC trial
Saturday, Dec. 11
5:30 - 7:30 PM CSTData from a Phase 1b study to assess the safety and tolerability of the investigational compound iniparib (BSI-201) in combination with irinotecan in patients with metastatic breast cancer (MBC)Iniparib Data:Abstract # P6-04-12
Activity in TNBC Cell lines
Sunday, Dec. 12
7:00 - 8:30 AM CSTData from a preclinical study assessing the cell cycle effects of the investigational compound iniparib (BSI-201) in combination