WorldCare Clinical, LLC (WCC), a leading imaging CRO focused on

maximizing the precision and accuracy of independent assessments in

clinical trials, today announced it is hosting a complimentary

conference on Imaging in Clinical Trials - Removing Bias and

Increasing Precision and Accuracy, which will be held on Friday, April

27, from 8:30 to 11:30 a.m. at the Holiday Inn Boston at Beacon Hill.

This complimentary conference is being held in conjunction with the

Imaging Biomarkers in Clinical Trials conference sponsored by the

Massachusetts General Hospital (MGH) Department of Radiology on April

27-28, 2012.

WCC's complimentary session will feature its own in-house experts, who

will discuss the operational considerations for conducting imaging

clinical trials and the value of a blinded independent central review

(BICR), including when and why to include one in a study design.

Additionally, they'll examine the importance of reader training,

testing and variability monitoring, as well as innovative digital

solutions for optimizing workflow and site management.

Imaging Biomarkers in Clinical Trials: Current Practice & Future

Trends, which will be held in the O'Keefe Auditorium at MGH in Boston,

is a two-day conference featuring keynote speaker Dwaine Rieves, MD,

director of the FDA's Division of Medical Imaging Products, and

experts from MGH. Speakers will review the current practice of imaging

biomarkers in clinical trials in oncology, cardiovascular, metabolic,

bone and joint diseases and highlight advanced imaging techniques that

have potential as surrogate biomarkers.

Imaging biomarkers serve as important endpoints for clinical trials in

the approval process for therapeutic drugs. Various criteria have been

developed for objective interpretation of imaging studies.

Additionally, there are emerging imaging techniques that have the

potential for applications as surrogate endpoints for clinical trials.

This conference will provide valuable insight for medical directors,

physicians, and PhD scientists at academic medical centers,

pharmaceutical companies, contract research organizations, and

biotechnology companies that design and manage clinical trials, as

well as radiologists who interpret images and non-radiologists

involved in imaging clinical trials. Attendees will hear from experts

on the latest imaging criteria, including RECIST and WHO, novel

imaging biomarkers and emerging modalities like PET/MR, elastography,

DCE, and perfusion being used in drug development.

The educational format of the conference will give attendees an

opportunity to hear from leading experts and participate in Q&A

sessions on topics relating to imaging biomarkers and advanced imaging

techniques. Additionally, case studies of previous clinical trials and

their successes and failures will be referenced.

For more information or to register for WCC's free conference, visit:

To view the conference agenda or to register for the MGH conference,


About WorldCare ClinicalWorldCare Clinical (WCC) is a leading imaging

CRO that employs imaging expertise, innovative technology and

operational excellence to maximize the precision and accuracy of a

blinded independent central review of clinical trial data. Originally

founded in 1992 by the Massachusetts General Hospital (MGH) Department

of Radiology, WCC has evolved as an independent company while

maintaining a strategic relationship with MGH. With a 20-year focus on

imaging trials and their specific requirements, WCC provides sponsors

with extensive medical, operational, and image management expertise in

support of even the most complex study designs. For more information,


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