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BEIJING--(BUSINESS WIRE)--Aug 21, 2012--Bonovo® Orthopedics, Inc. announced today that it has launched the first PEEK (PEEK-OPTIMA ® polymer from INVIBIO ® ) lateral interbody fusion cage, Cross-Fuse® in China. Minimally Invasive Lateral Interbody Fusion (MILIF) had been gaining increasing popularity in the U.S. and Europe due to its less invasive nature and proven safety and effectiveness.

According to Chip Bao, Ph.D., Bonovo’s Chief Executive Officer, “We feel extremely privileged to be the first to introduce this new technology into China so Chinese patients can benefit from this minimally invasive surgical treatment with proven clinical results. The speed of approval through the SFDA of this important therapy is a testament to the expertise of the Bonovo clinical and regulatory team.” Professor Xifeng Zhang, M.D., Director of Minimally Invasive Surgery (MIS) of the Orthopedic Department at 301 Hospital in Beijing, successfully performed the first Cross-Fuse® surgery at 301 Hospital in China with Dr. John Regan, a world renowned spine surgeon specializing in MIS. Professor Zhang stated, “Many Chinese surgeons have been waiting for this new technique for a long time so they can apply this minimally invasive surgery to their patients. Like the rest of the world, MIS has become a strong trend in China. In general, Chinese patients tend to favour conservative care or less invasive surgeries. With the SFDA approval of Cross-Fuse®, I am glad that Chinese surgeons finally have another minimally invasive surgical option to treat their patients with lumbar degenerative disc disease.” Cross-Fuse® is manufactured by Pioneer Surgical Technology, Inc. (Marquette, MI), a key business partner of Bonovo Orthopedics. Cross-Fuse® is made of polyether ether ketone (PEEK), a biomaterial with proven biocompatibility and properties similar to that of human bone.

About Bonovo Bonovo Orthopedics, Inc. develops, manufactures and sells orthopedic implants and other orthopedic products to the Chinese healthcare market. Bonovo is a China-based company with a 17 year history as a pioneer in the Chinese orthopedic industry. Bonovo has two ISO-certified manufacturing facilities, world-class R&D capabilities and one of the leading distribution networks in the Chinese orthopedics industry.

The Bonovo team leverages its unique product development capability and its wide connections with the West to bring the latest technologies to the China market. Bonovo’s wide range of products includes spinal implants, artificial joints, pain management products and minimally invasive surgical solutions. The Company distributes Bonovo-branded products and serves as the distributor in China for other leading international orthopedic companies.

Through its Bonovo Academic Alliance™, its organization dedicated to enhancing the connection between Eastern and Western surgeons, the Bonovo team offers Chinese surgeons and the spine community unparalleled access to western technology and key opinion leaders. The Bonovo Academic Alliance™ offers fellowship programs, international symposia, summits and unique surgeon training opportunities.

Through its unique products and programs, Bonovo Orthopedics is committed to driving new standards of orthopedic care throughout China. For more information go to www.bonovo-ortho.com.

About Pioneer Surgical Technology, Inc. Pioneer Surgical Technology was founded in Marquette, Michigan in 1992. Since that time, Pioneer Surgical has developed successful products in the Spine, Biologics, Orthopedics, and Cardio-Thoracic markets. Pioneer has several facilities throughout the U.S. and Europe and employs nearly 300 people. Pioneer’s state-of-the-art manufacturing capabilities differentiate it from others in the marketplace. This vertically-integrated structure greatly enhances Pioneer’s ability to take an idea from the drawing board to commercialization. Pioneer demonstrates its commitment to surgical innovation by designing and delivering products that provide intraoperative efficiency for surgeons, cost-effectiveness for the healthcare system and better outcomes for patients. For more information on Pioneer and its products, visit http://www.pioneersurgical.com.

CONTACT: Bonovo Orthopedics, Inc.

Chip Bao, Ph.D.

Chief Executive Officer +86-10-5190 6561 (China) 952-886-7106 (US) www.bonovo-ortho.com KEYWORD: UNITED STATES ASIA PACIFIC NORTH AMERICA CHINA NEW YORK INDUSTRY KEYWORD: SURGERY HEALTH MEDICAL DEVICES MEDICAL SUPPLIES PHYSICAL THERAPY SOURCE: Bonovo Orthopedics, Inc. Copyright Business Wire 2012 PUB: 08/21/2012 02:19 AM/DISC: 08/21/2012 02:19 AM http://www.businesswire.com/news/home/20120820006453/

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