CORAL SPRINGS, Fla., Aug. 7, 2012 /PRNewswire/ -- Digestive CARE™, a medical group of 52 gastroenterologists in Broward and Palm Beach County, today announced that they are the first gastroenterology group in South Florida to offer Fecal Transplant therapy to patients with Fulminant or Refractory Pseudomembraneous Colitis.
Pseudomembranous colitis has dramatically increased in frequency and severity over the past ten years. Coincident with this, a dramatic increase has been seen in refractory, relapsing, and fulminant cases. In addition, a new hypervirulent strain of C. Dif (NAP1/B!/027) has been implicated in several outbreaks since the early 2000's. This strain may be particularly refractory to standard antibiotic treatment. As many as 11% of patients infected with the hypervirulent strain of C. Dif may experience complications including shock, need for colectomy, megacolon, perforation and even death within a 30 day period. Gastroenterologists have all experienced diminishing returns with standard antibiotic protocols.
Fecal bacteriotherapy (i.e. fecal transplant) involves instillation of healthy donor stool via colonoscope, enema, or nasojejunal tube into the alimentary tract of the patient. There are nearly 275 studied cases of fecal bacteriotherapy. All patients suffered from either refractory, recurrent, or fulminant disease. Seventy five percent of cases involved instilling donor stool via colonoscopy. The cumulative success rate in this extremely challenging patient cohort is reported to be 89%. This success rate reaches 98% when an additional infusion is administered in the few patients who fail to respond to initial treatment.
Digestive CARE™ is pleased to offer this service at Boca Raton Regional Hospital. Appropriate patients include those with refractory, recurrent, or fulminant disease. Please see below for inclusion criteria.