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A look at the most acquisitive medical device companies, culled from MassDevice.com's Big 100 database of more than 1,300 medical device industry transactions.

MassDevice.com Big 100

More than $50 billion was spent on acquisitions by Big 100 medical device companies from the beginning of 2011 through the 1st half of 2012.

Johnson & Johnson (NYSE:JNJ) made the biggest splash with its nearly $18.4 billion acquisition of Synthes – surpassing the total value of all deals made in 2009. It alone accounts for almost 37% of the total value of deals made over the past 18 months. And J&J also dwarfed the competition in terms of the number of deals struck, at 13.

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