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A look at debt-to-equity ratios for the top medical device companies, culled from MassDevice.com's Big 100 database.

We're looking at debt-to-equity ratios, which measure how aggressively a company finances its growth using debt. It's an important metric, especially during rough economic patches, because highly leveraged companies run the risk of not generating enough growth to outweigh the cost of the debt – which could lead to bankruptcy.

Here's a look at the 5 highest debt ratios among the pure-play medical device companies on our Big 100 list:

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