TBI is one of the most common causes of death and disability in the world, usually resulting from blasts, falls, knocks, traffic accidents, and assaults.
The proposed diagnostic tool is a fully-integrated, automated biosensor device which requires only a drop of blood to detect up to three biomarkers released by the brain after sustaining injury. The biomarker readings will be displayed on an easy-to-read screen, along with an indicator alerting the care giver to the severity of the injury.
Unlike conventional diagnostic tools such as neurological tests and computed tomography (CT) scans, the biosensor device does not require any trained personnel for sample handling. The portable feature of the device facilitates rapid on-site diagnosis of the injury. Caregivers will be able to respond quickly with the proper course of treatment to prevent injury aggravation.
A*STARs Institute of Microelectronics (IME) and SFC Fluidics®, a USA microfluidics-based biomedical device development company, will be collaborating to develop a portable diagnostic tool for rapid triaging of traumatic brain injury (TBI) victims and to improve the treatment strategies.