Most traditional CW 532 nm lasers based on Nd:YVO4 crystals suffer from higher output noise because the intracavity doubling mechanism causes a well-known phenomenon called green noise. In contrast, the OPSL has a very short upper state lifetime which naturally eliminates green noise completely without additional measures, such as complex single longitudinal mode operation. Together with its high output power, this makes these Sapphire 532 lasers ideal for fast-throughput applications based on accurate measurements of relative fluorescence intensity.
Specific applications for Sapphire 532 lasers span several areas of bio-instrumentation that utilize fluorophores optimized for 532 nm excitation. These include DNA sequencing, flow cytometry, confocal microscopy, and high-throughput drug discovery.